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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '773e64f528b32e07349d95934b6583796ff27ae3d28347292931074ac0df3544' 
  AND token = 'd5deYu+Tver7fhRp0h3zqPIDnXjlMzPpL85sncjSo54=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}