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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '01cd8eda67ee871e47840c98e3ac1fb96f661c462db64a3ce9037bef15f25a60' 
  AND token = 'Ja28ve6CrG/bOUtHHFwq09tdiA7Pb/U9UWgnZNdFIk0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}