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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7178ece4db200cd36b91e8e41f17e57630aae4a08f4c71776b6cea03d74d8445' 
  AND token = 'mlnQfxu1l0XrjWvxJHHiZkH3u1S3GlWkNXO/BhosDMw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}