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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fa5be4232af6d4ada4df529f20192b584225cde41da67d4e680a314605092650' 
  AND token = 'iqu7w1aXr03bH48msWlbTy2XQD4+6c1DbjM98LometE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}