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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cc086b8e19a61d25dc974e8138e80012d0c3b09e47dc27120c5117ace850f418' 
  AND token = 'c/q0wMzhYzIyyKiy3narCK09P+uSQlIF6BRcG6GSJSU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}