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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9744f41adf6e3b690a3f21cd7fbfee1f61d76430340cf6d05b204c3cacfeccab' 
  AND token = 'Fb7zq6jQ10/lo+Q57x/Qk/3tI7IiIqfDJwRcgfcwrEo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}