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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c2d9014e53290f700f7558c727f016b80b70f1ecccb7f9bc0ab45bce39431111' 
  AND token = 'KZbDZTCcXtIV1GQkEONdMO4I/Da33YvcxxI6+BxBM5w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}