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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e8051021b5f47055a16ea05b4c448f1d5d860a88da9f9e2ba86c166befee1b5d' 
  AND token = 'XBnWjNklbNqNZaDwEpL/hrHgdEKhFAPkxh8d/dvXNiM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}