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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '864acf0381520006c8e0fd0c174f8137c3bb12ab3a45bb7a2a7e50cfeb6823b0' 
  AND token = 'tqIFpNG76KCZxQD++DWcgZbeKfkgRmbNVQBEAHvzIB4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}