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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80452e16e890ac7d7f19b1f3faa934f94b5ae6cab5ae8be3c9fc1693aaa82cdc' 
  AND token = '45LKD8JGXj06uvsBq/qibwWSjQ6XeIbqBLqSOG8hb1Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}