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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6f9e92ca8562c1402b4fe051ade299fd57a5446b881671f5002f642a370e50ac' 
  AND token = 'fsx5iWUSUs2h4LXvWB9JxCMvaHi43UuDFlm8/EuDods=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}