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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd390c952bf825acde2795a06ec03d3af98c9282a12b44c7baa9fbcdd098db85c' 
  AND token = 'G+0VZphXps1GeVmSKYROHZPeENNP8LnTWgrYwCpRWR0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}