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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bc44b49cbdf3bb3bcfa287ee32da1b0dc8cb285d8d21d017a5514ca4f152c127' 
  AND token = '5ApmU7ZUlgSy/66TS/vfcTNxdUmwKS1hYr5KHb+XFLM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}