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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4778c8021071e3c46d5af553731eb3cb9574162f07c57215fd8ed38daaa2d87e' 
  AND token = '1VIZ6CdSyWCDInfNCXTJ9OmFLGjm+9o/hZWHLDtEaCs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}