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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '26566a0cc31e3ca189831b4bf10c7a7df5fbe55625e176dafd1431b5daf14980' 
  AND token = 'hP9u0g/xWqB/HaVROH7ZQc5GHvcDeT/+x8ouN3SABkU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}