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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b8f410fc46723ac16efd5bd02b66a48da4ee926813c78308248ac604db72b60a' 
  AND token = 'QWWZqaGqx+7K+AA8rn/qW8TeF9BJN3WObU7Eufl05To=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}