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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '900080b0385d8df74574b2c18af66485a27a958eb494ac0bd1f92269a29de608' 
  AND token = 'BTDWcJeNEgB/7yrGTTfOopazXOKZ0LNq2u5m391QMeg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}