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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f1b1c5e8e9732922efa4dabc46b127c5f0654bcb05f76e598484abe4ebadeb60' 
  AND token = 'kiIYcyg77dagm2QE9FI8Ne+VhhJxXdOnC+eLSSm+UnI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}