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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e142ff38ab14bcf52f0f1bb2a309675556fa51529226a9b1e5096881b5049a26' 
  AND token = 'ubUQOmOH9s0bwyYWYyacj9THxwV2f+MvRFDo24GfSfE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}