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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0b50879b2570d84892c267ed77b910f8c6cddaef8e84c7f82b2157f5fb02b5ca' 
  AND token = 'Uy/lEzJrV0KYNuGavy9ZmsTv0dO/vJG6l/TsXhXsKEc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}