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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8cacf8b9a3bab15d24781d6fc10b8ca905cf9bac2e8193a5e5b5393d46d59206' 
  AND token = 'u4r9x3MOYjQxLqak84kdN77K07VrEU88DBP29RxSvIw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}