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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bbe7a6aed5c286456452414840b341222615d23f21a4fcb2a0af1a83576e0ba7' 
  AND token = 'PDbJB8Avk7pkNsf4jtCeBa9CZuoZ5L3OXexcwp0yZqo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}