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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ec8f3ac281a67c81dcf2dc5749fa3943d1d3ff357394d163d546d00b98b753d' 
  AND token = '83fpHLbxpA0tkUZBfC8t42uilxg66P+layeSGiYlQdY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}