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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b89ff863f6f0404cfb5974afe781f6509f41e2c7b2fc1a5ce5ff88cf854bdd9' 
  AND token = '7WNFV/kh297o0gq+wIfbClxOCyD8Mebro0cHGngmyi4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}