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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '445f449021787051e33c4b696018d92e8cd415ca787c8a893ecd1fc0837d7280' 
  AND token = 'uF3XKHu0J25tAe/SkBi+BzqIsgeccDw9mIwLM4gUYgQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}