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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1f7f3a2ef9cc79b317a15216f00dcbfb4cc13c6be8884c23d95efc4112e76d26' 
  AND token = 'NsPn09ZWK6kEejG147zCkHlFii6lY6cXTW594zEe7Gk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}