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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8749daca2e94517efc5fb85f06dd6e12feeea8605eeb53b72f31cee1603c0fef' 
  AND token = 'aDlqo9nb+2KvejuqJxU9YRNTY4YLPMdu3rSiU9BHruw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}