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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '42f7f10dd556440f74e38db710ffe325a3a43a0a34003652b28f96fcc5ed0e83' 
  AND token = 'LXCN3o/Ewe35xuhzwLUtof+BNIDpAoDSUtcis1MMod8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}