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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd50c6b3762e6614ee1e2df1d0586a27c96e889f6fc7fc0be91f171ac10703381' 
  AND token = 'V9KREFgOFzdD9qZRmdeZfEON0sItE8yyBcoUum/gXgk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}