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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78dc30216738b1fe18f264b4f87a4e5a52be4b8ba4fadaeadf0dec8171735dc9' 
  AND token = 'C7M7R5E61xUHUEkaH/XMSWsSX9+nCowKzR3yhI1I1M0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}