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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '827d187d10233dd8ea686bca599688b3060cfef40d509ddb958d46bed394f299' 
  AND token = '4YHBtHf5Sas7sudP1sRCAdvb69xUrMmMjBuvcFW8xX0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}