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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0a5b3a91fee8db3836d441f3b191d1dd2740923544d582fc7ebabff68cdadf03' 
  AND token = '9I9VQf1A+4YF/fSOuxONidnXcqHO3/Jjp8tFlRuWHZI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}