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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8167f4507b4b25ba6be04fd32877e2f5fa1adcbe5e1949e48b161d117c7505ee' 
  AND token = 'CY24ca5JullEwn5gGdBERiyVCEdU+3XyVqSw4ryRVLg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}