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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ddc49ff7e00a1ebfd7c6b22dd229e57f7ee82aa7ca97c181e4b4ad5c650e042' 
  AND token = 'pPXszSeYt/FNt6thrBVkEKb9en6TLOCtOK3u18Wc4RY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}