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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '52ddaf06a881508b82067350d23510b9cfd8e5caca64f3223c04dbd65e370eed' 
  AND token = '0+2I2nzIycrtfMOruWwHk/ZBJ0np5Kq9bHwZWDnKU8s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}