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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b01985af713e30e7676415be6c3d615f4c13cf51ee319bdd6b4607e752b0aa05' 
  AND token = '8ls+b9XJGr+q/K8aMdJuL+EOPybPwMVmjSwofokFTNU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}