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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8afff38cdeeacb23e7616383fd7b3ecb8dfd0b46bbf2867b3ae9f93e4d2dd049' 
  AND token = '9e6tx/H74UEtPuD77nSMMk7W8cEZE0i3HiESoRCAPjM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}