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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2319dd53eb89df37529900ae53f3b35b5dc3ba99b6a99011979ed1c75dc02bb6' 
  AND token = 'WLNIOtYiWXAtMvmT7gF3WFIlMCBSsPAhBa/Kr1XhD+M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}