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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53f2199e1e5430892a81c641c2ff16c9b0c50b6fb91b48f22a94eb4a89bc3a4b' 
  AND token = 'JOB8bRpmH/3tZLRCOeN6H4Q1bAVPoEGOlPpj90Rbkow=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00060

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}