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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4bf0781e6ec4ffcadcd167c303969e108c6f6e9617f01c229ea5dcc1ace8eb91' 
  AND token = 'u4/eHjmnarX5HwAxUtTXiZgpy4Y4LrXv2fZfs9un62Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}