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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d263c27cfc0473e756e609f5a0db4830638659a4b36b5770f457370b9362978' 
  AND token = 'kwR/QwrKu8eQp7SzBGP65plZM18i6Qsu7hfgQBPzY4Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00057

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}