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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e1d53e8371d47aa06a92b1b696f4e0e8363d2dc81988744c266ea063f24b8f9' 
  AND token = 'ufhctBkVy9foESOSIx1JkMdjtfb+5g0R4QUw47NApBQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}