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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ab2beb8333817bfdfe79e1037d95dc1bb1ff3920beb614b6599485e31f00c07' 
  AND token = 'ELMEaRemLUFHI7Ilm4HCzHDgY7hzTvf/mgmrMmpRs/k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}