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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '42a58637d4a63a8e250d78e98a9c21f1f090482d8468bdee17b8571035370bf1' 
  AND token = 'mvC1wa53ATpGT1IGdGkBbrp/CY/yb1kd0WcyRt+t7Qw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}