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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a01c9216af3ccdbe38f98f01d509d0fbfbc311200779b57c7e30fa0d2a37bbdd' 
  AND token = '1ZjutyYxq1L7KL0FfMtV7xM/MS3cAN6sd9OjL9tKmRg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}