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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9122e47d9fb25fc16722495c24f6c9f466bac94b840d6ca86c66f5a282077e90' 
  AND token = 'uxXEPZm6mUE3AoRt5BKwTFFeXOMmy7kuNdkCwBoqAfM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}