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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7aff28bfc7ef7d3af476279ef294c63e2cbcf55eceb5a26ba9da4464abb66ccd' 
  AND token = 'XCtvG25tYTszBSWn/k+XI77jnytB2MoDeyqcXlPE6E0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}