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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd26ad9b4548c1535bcde63d0f24f030caf428c88fe5bdb1f381a93011c8c45e9' 
  AND token = 'ZgFiBV/kDKiNihNe8lv6T+rZHpRTHnWAF/lL7VgK814=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}