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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c60c82cbc7c27c8ed40696c787cbbe3915ac38ee536380286fdc65850c4aa188' 
  AND token = 'b+5SbG9UzNVx+vzzf5I3wYXsYhyAKo3AFtcV2+VXG1E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}