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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '850b81a6d07c61e38e6175ae582ef72795c62c789e5cf74c75c1f1d750e4b9c5' 
  AND token = 'SSWTm4OL7QCDEiCHjF3SyOQ8CbNd8J9OeC80gK9Ncu8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}